VMD is a molecular graphics program designed for the display and analysis of molecular assemblies, in particular biopolymers such as proteins and nucleic acids. VMD can simultaneously display any number of structures using a wide variety of...
Summary: The Sequence Alignment/Map (SAM) format is a generic alignment format for storing read alignments against reference sequences, supporting short and long reads (up to 128 Mbp) produced by different sequencing platforms. It is flexible in style,...
The CES-D scale is a short self-report scale designed to measure depressive sym ptomatology in the general population. The items of the scale are sym ptoms associated with depression which have been used in previously validated longer...
A tetrazolium salt has been used to develop a quantitative colorimetric assay for mammalian cell survival and proliferation. The assay detects living, but not dead cells and the signal generated is dependent on the degree of activation...
Systematic reviews and meta-analyses have become increasingly important in health care. Clinicians read them to keep up to date with their specialty,1 2 and they are often used as a starting point for developing clinical practice guidelines....
Systematic reviews and meta-analyses can provide convincing and reliable evidence relevant to many aspects of medicine and health care.1 Their value is especially clear when the results of the studies they include show clinically important effects of...
The hallmarks of cancer comprise six biological capabilities acquired during the multistep develop-ment of human tumors. The hallmarks constitute an organizing principle for rationalizing the complexities of neoplastic disease. They include sustaining proliferative signaling, evading growth suppressors,...
Maximum likelihood or restricted maximum likelihood (REML) estimates of the pa-rameters in linear mixed-effects models can be determined using the lmer function in the lme4 package for R. As for most model-fitting functions in R, the model...
A method has been devised for the electro-phoretic transfer of proteins from polyacrylamide gels to ni-trocellulose sheets. The method results in quantitative transfer of ribosomal proteins from gels containing urea. For sodium dodecyl sulfate gels, the original...
This paper presents a method for extracting distinctive invariant features from images that can be used to perform reliable matching between different views of an object or scene. The features are invariant to image scale and rotation,...